Thoroughly mining the existing scientific evidence is a critical first step for your product development program. Evidera’s team of researchers has decades of experience in evidence review and synthesis, from the most basic literature reviews to cutting-edge and complex methods that can extract useful information from even the most disparate sources. We publish our studies regularly and have completed 30+ studies that have been incorporated into regulatory or HTA submissions. We have also completed at least 20 literature reviews in nearly every major therapeutic area, including 70+ reviews in oncology, 50+ in neurology and 40+ in cardiovascular.

Evidera will help you gain an understanding and unlock the value of published and “grey” literature to:

  • Capitalize on existing research while assessing evidence gaps
  • Support planning for evidence development
  • Derive inputs for economic modeling for HTA submissions
  • Inform study design and planning for primary research (e.g., selection of clinical efficacy endpoints or comparators) to facilitate future meta-analyses
  • Estimate comparative effects versus competitors when direct head-to-head data are not available
  • Quantify the reported burden-of-illness for dossiers and payer submissions
  • Detect early warnings of adverse events associated with a product

Any of these tasks can be part of an ongoing “surveillance” of the literature.


Network Meta-Analysis

Understand the relative effectiveness of a product or treatment via a quantitative assessment of the available literature.

Literature Reviews

Understand clinical, epidemiological and/or health economic evidence via a systematic or targeted qualitative review of the available literature.

Evidence Surveillance and Social Media Review

Understand real-world outcomes by reviewing information from various social media sources, pharmacovigilance feeds, market intelligence updates, etc.

Evidence Mapping

Facilitate more efficient literature searching by mapping themes in existing literature.

Rapid Literature Reviews

Conduct fast, focused epidemiology and safety literature reviews to meet internal/external evidence needs in just days.

Novel Approaches to Indirect Comparison: Simulated Treatment Comparisons (STC) and Matching-Adjusted Indirect Comparisons (MAIC)

Use targeted comparisons to overcome challenges of traditional methods for indirect treatment comparison without compromising validity of results. Click here for more info.

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